Yes, Sean, I switched on Computer TWO to Genius Wired Mouse and the issue is still occuring. Before I switched, I tried the both drivers for Microsoft Wireless Mouse - defalut drivers that came with Windows and MS dedicated drivers (exactly as from your link).
To be honest, I cannot analyze in my mind what configuration can cause the issue (and I am good in analyzing, it is half of my job). Evidently, mouse drivers and whole new PC dont influence it.
Last weeks, the issue occurs only on PCs (TWO and THREE) that has Win 10 Enterprise and are totally offline, but I cannot imagine how this could cause the issue.
(Today, I experienced also real transfer of element on simple mouse click. I have set 1 decimal place for px, work in px and the position was rounded from say 123,6 to 124 px on both axes.)