Thanks,
So to answer a few question raised:
Windows version: 23H2
I have tried installing using both MSIX and MSI/EXE installers. (all installations runs smooth wit the same end result)
I get the following errors in the event viewer, apparently related to .NET (both with Designer version 2.4.2 and Photo 2.5.7
Application Error
Faulting application name: Designer.exe, version: 2.4.2.2371, time stamp: 0x660d2be1
Faulting module name: KERNELBASE.dll, version: 10.0.22621.4751, time stamp: 0x2db246bf
Exception code: 0xe0434352
Fault offset: 0x000000000005fb4c
Faulting process id: 0x0x726C
Faulting application start time: 0x0x1DB6EFE3D5F858E
Faulting application path: C:\Program Files\WindowsApps\SerifEuropeLtd.AffinityDesigner2_2.4.2.2371_x64__3cqzy0nppv2rt\App\Designer.exe
Faulting module path: C:\windows\System32\KERNELBASE.dll
Report Id: 8e988b53-1329-4c8c-9554-3bd7267399a2
Faulting package full name: SerifEuropeLtd.AffinityDesigner2_2.4.2.2371_x64__3cqzy0nppv2rt
Faulting package-relative application ID: SerifEuropeLtd.AffinityDesigner2
.NET Runtime
Application: Designer.exe
Framework Version: v4.0.30319
Description: The process was terminated due to an unhandled exception.
Exception Info: System.UnauthorizedAccessException
at System.IO.__Error.WinIOError(Int32, System.String)
at System.IO.Directory.InternalCreateDirectory(System.String, System.String, System.Object, Boolean)
at System.IO.Directory.InternalCreateDirectoryHelper(System.String, Boolean)
at Serif.Interop.Persona.Application.EnsureDirectoryExists(System.String)
at Serif.Interop.Persona.Application.get_AppDataPathForAllUsers()
at Serif.Interop.Persona.Application..ctor()
at Serif.Affinity.Application..ctor()
at Designer.Application.Main(System.String[])
These are the installed .NET versions
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\NET Framework Setup\NDP\CDF
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\NET Framework Setup\NDP\v2.0.50727
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\NET Framework Setup\NDP\v3.0
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\NET Framework Setup\NDP\v3.5
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\NET Framework Setup\NDP\v4
HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\NET Framework Setup\NDP\v4.0