I have the same issues. I can not read the menu text or icons on my High-Resolution monitor. No matter how I attempt to correct the situation, it does not resolve. My eyesight suffers when using this application. My vision is blurred from eye-strain. At this point, I am ready to throw my hands up in the air and return to Photoshop. To say I am extremely disappointed in Affinity is an understatement. I can work on a lower-resolution monitor, but that defeats the purpose of a high-resolution monitor when creating graphic art. Totally unacceptable. This has been going on for YEARS. Unbelievable.