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I was able to fix the problem. Apparently something was wrong with the Studio, clicking the View menu > Studio > Reset Studio and restarting fixed it.

Today - quite suddenly - Affinity Designer v1.10.5.1342 running under Windows 10 has started crashing shortly after startup when clicking menus, or when attempting to open any .afdesign file. There are no error messages, the window simply disappears. I've tried uninstalling & re-installing, but that did not help. The Windows Application Event Log shows the following error related to the crash: Application: Designer.exe Framework Version: v4.0.30319 Description: The process was terminated due to an unhandled exception. Exception Info: System.NullReferenceException at Serif.Affinity.Commands.FloatAllWindowsCommand.CanExecute(System.Object) at MS.Internal.Commands.CommandHelpers.CanExecuteCommandSource(System.Windows.Input.ICommandSource) at System.Windows.Controls.MenuItem.UpdateCanExecute() at System.Windows.Controls.MenuItem.OnCommandChanged(System.Windows.Input.ICommand, System.Windows.Input.ICommand) at System.Windows.Controls.MenuItem.OnCommandChanged(System.Windows.DependencyObject, System.Windows.DependencyPropertyChangedEventArgs) at System.Windows.DependencyObject.OnPropertyChanged(System.Windows.DependencyPropertyChangedEventArgs) at System.Windows.FrameworkElement.OnPropertyChanged(System.Windows.DependencyPropertyChangedEventArgs) at System.Windows.DependencyObject.NotifyPropertyChange(System.Windows.DependencyPropertyChangedEventArgs) at System.Windows.DependencyObject.UpdateEffectiveValue(System.Windows.EntryIndex, System.Windows.DependencyProperty, System.Windows.PropertyMetadata, System.Windows.EffectiveValueEntry, System.Windows.EffectiveValueEntry ByRef, Boolean, Boolean, System.Windows.OperationType) at System.Windows.DependencyObject.InvalidateProperty(System.Windows.DependencyProperty, Boolean) at System.Windows.Data.BindingExpressionBase.Invalidate(Boolean) at System.Windows.Data.BindingExpression.TransferValue(System.Object, Boolean) at System.Windows.Data.BindingExpression.Activate(System.Object) at System.Windows.Data.BindingExpression.AttachToContext(AttachAttempt) at System.Windows.Data.BindingExpression.MS.Internal.Data.IDataBindEngineClient.AttachToContext(Boolean) at MS.Internal.Data.DataBindEngine+Task.Run(Boolean) at MS.Internal.Data.DataBindEngine.Run(System.Object) at System.Windows.ContextLayoutManager.fireLayoutUpdateEvent() at System.Windows.ContextLayoutManager.UpdateLayout() at System.Windows.Interop.HwndSource.SetLayoutSize() at System.Windows.Interop.HwndSource.set_RootVisualInternal(System.Windows.Media.Visual) at System.Windows.Controls.Primitives.Popup.SetRootVisualToPopupRoot() at System.Windows.Controls.Primitives.Popup.CreateWindow(Boolean) at System.Windows.Controls.Primitives.Popup.OnIsOpenChanged(System.Windows.DependencyObject, System.Windows.DependencyPropertyChangedEventArgs) at System.Windows.DependencyObject.OnPropertyChanged(System.Windows.DependencyPropertyChangedEventArgs) at System.Windows.FrameworkElement.OnPropertyChanged(System.Windows.DependencyPropertyChangedEventArgs) at System.Windows.DependencyObject.NotifyPropertyChange(System.Windows.DependencyPropertyChangedEventArgs) at System.Windows.DependencyObject.UpdateEffectiveValue(System.Windows.EntryIndex, System.Windows.DependencyProperty, System.Windows.PropertyMetadata, System.Windows.EffectiveValueEntry, System.Windows.EffectiveValueEntry ByRef, Boolean, Boolean, System.Windows.OperationType) at System.Windows.DependencyObject.InvalidateProperty(System.Windows.DependencyProperty, Boolean) at System.Windows.StyleHelper.InvalidateDependents(System.Windows.Style, System.Windows.FrameworkTemplate, System.Windows.DependencyObject, System.Windows.DependencyProperty, MS.Utility.FrugalStructList`1<System.Windows.ChildPropertyDependent> ByRef, Boolean) at System.Windows.StyleHelper.OnTriggerSourcePropertyInvalidated(System.Windows.Style, System.Windows.FrameworkTemplate, System.Windows.DependencyObject, System.Windows.DependencyProperty, System.Windows.DependencyPropertyChangedEventArgs, Boolean, MS.Utility.FrugalStructList`1<MS.Utility.ItemStructMap`1<System.Windows.TriggerSourceRecord>> ByRef, MS.Utility.FrugalMap ByRef, Int32) at System.Windows.FrameworkElement.OnPropertyChanged(System.Windows.DependencyPropertyChangedEventArgs) at System.Windows.DependencyObject.NotifyPropertyChange(System.Windows.DependencyPropertyChangedEventArgs) at System.Windows.DependencyObject.UpdateEffectiveValue(System.Windows.EntryIndex, System.Windows.DependencyProperty, System.Windows.PropertyMetadata, System.Windows.EffectiveValueEntry, System.Windows.EffectiveValueEntry ByRef, Boolean, Boolean, System.Windows.OperationType) at System.Windows.DependencyObject.SetValueCommon(System.Windows.DependencyProperty, System.Object, System.Windows.PropertyMetadata, Boolean, Boolean, System.Windows.OperationType, Boolean) at System.Windows.DependencyObject.SetCurrentValueInternal(System.Windows.DependencyProperty, System.Object) at System.Windows.Controls.Primitives.MenuBase.OnIsSelectedChanged(System.Object, System.Windows.RoutedPropertyChangedEventArgs`1<Boolean>) at System.Windows.RoutedEventArgs.InvokeHandler(System.Delegate, System.Object) at System.Windows.RoutedEventHandlerInfo.InvokeHandler(System.Object, System.Windows.RoutedEventArgs) at System.Windows.EventRoute.InvokeHandlersImpl(System.Object, System.Windows.RoutedEventArgs, Boolean) at System.Windows.UIElement.RaiseEventImpl(System.Windows.DependencyObject, System.Windows.RoutedEventArgs) at System.Windows.Controls.MenuItem.OnIsSelectedChanged(System.Windows.DependencyObject, System.Windows.DependencyPropertyChangedEventArgs) at System.Windows.DependencyObject.OnPropertyChanged(System.Windows.DependencyPropertyChangedEventArgs) at System.Windows.FrameworkElement.OnPropertyChanged(System.Windows.DependencyPropertyChangedEventArgs) at System.Windows.DependencyObject.NotifyPropertyChange(System.Windows.DependencyPropertyChangedEventArgs) at System.Windows.DependencyObject.UpdateEffectiveValue(System.Windows.EntryIndex, System.Windows.DependencyProperty, System.Windows.PropertyMetadata, System.Windows.EffectiveValueEntry, System.Windows.EffectiveValueEntry ByRef, Boolean, Boolean, System.Windows.OperationType) at System.Windows.DependencyObject.SetValueCommon(System.Windows.DependencyProperty, System.Object, System.Windows.PropertyMetadata, Boolean, Boolean, System.Windows.OperationType, Boolean) at System.Windows.DependencyObject.SetCurrentValueInternal(System.Windows.DependencyProperty, System.Object) at System.Windows.Controls.MenuItem.MouseEnterHelper() at System.Windows.RoutedEventArgs.InvokeHandler(System.Delegate, System.Object) at System.Windows.RoutedEventHandlerInfo.InvokeHandler(System.Object, System.Windows.RoutedEventArgs) at System.Windows.EventRoute.InvokeHandlersImpl(System.Object, System.Windows.RoutedEventArgs, Boolean) at System.Windows.UIElement.RaiseEventImpl(System.Windows.DependencyObject, System.Windows.RoutedEventArgs) at System.Windows.ReverseInheritProperty.FirePropertyChangeInAncestry(System.Windows.DependencyObject, Boolean, MS.Internal.DeferredElementTreeState, System.Action`2<System.Windows.DependencyObject,Boolean>) at System.Windows.ReverseInheritProperty.FirePropertyChangeInAncestry(System.Windows.DependencyObject, Boolean, MS.Internal.DeferredElementTreeState, System.Action`2<System.Windows.DependencyObject,Boolean>) at System.Windows.ReverseInheritProperty.OnOriginValueChanged(System.Windows.DependencyObject, System.Windows.DependencyObject, System.Collections.Generic.IList`1<System.Windows.DependencyObject>, MS.Internal.DeferredElementTreeState ByRef, System.Action`2<System.Windows.DependencyObject,Boolean>) at System.Windows.Input.MouseDevice.ChangeMouseOver(System.Windows.IInputElement, Int32) at System.Windows.Input.MouseDevice.PreNotifyInput(System.Object, System.Windows.Input.NotifyInputEventArgs) at System.Windows.Input.InputManager.ProcessStagingArea() at System.Windows.Input.InputManager.ProcessInput(System.Windows.Input.InputEventArgs) at System.Windows.Input.InputProviderSite.ReportInput(System.Windows.Input.InputReport) at System.Windows.Interop.HwndMouseInputProvider.ReportInput(IntPtr, System.Windows.Input.InputMode, Int32, System.Windows.Input.RawMouseActions, Int32, Int32, Int32) at System.Windows.Interop.HwndMouseInputProvider.FilterMessage(IntPtr, MS.Internal.Interop.WindowMessage, IntPtr, IntPtr, Boolean ByRef) at System.Windows.Interop.HwndSource.InputFilterMessage(IntPtr, Int32, IntPtr, IntPtr, Boolean ByRef) at MS.Win32.HwndWrapper.WndProc(IntPtr, Int32, IntPtr, IntPtr, Boolean ByRef) at MS.Win32.HwndSubclass.DispatcherCallbackOperation(System.Object) at System.Windows.Threading.ExceptionWrapper.InternalRealCall(System.Delegate, System.Object, Int32) at System.Windows.Threading.ExceptionWrapper.TryCatchWhen(System.Object, System.Delegate, System.Object, Int32, System.Delegate) at System.Windows.Threading.Dispatcher.LegacyInvokeImpl(System.Windows.Threading.DispatcherPriority, System.TimeSpan, System.Delegate, System.Object, Int32) at MS.Win32.HwndSubclass.SubclassWndProc(IntPtr, Int32, IntPtr, IntPtr) at MS.Win32.UnsafeNativeMethods.DispatchMessage(System.Windows.Interop.MSG ByRef) at System.Windows.Threading.Dispatcher.PushFrameImpl(System.Windows.Threading.DispatcherFrame) at System.Windows.Application.RunDispatcher(System.Object) at System.Windows.Application.RunInternal(System.Windows.Window) at Designer.Application.Main(System.String[]) Does anyone have any bright ideas as to what I should try next to get Designer working again? Thanks for any help!