I've also got the (almost) same issue, not only in Photo but also in Designer and Publisher. As soon as I copy any complex object (aka not text), my taskbar and programs like the task manager start to flicker like crazy. As soon as I clear the clipboard, or copy something simple like text, it's fine again. I couldn't reproduce that the menus also flicker this time, but I also had it that even in things like Chrome the entire window was refreshing, making it impossible to even type something into the address bar.
I'm using Affinity Publisher v1.10.4.1198 on Windows 11 21H2 (Build 22000.318), with an Ryzen 7 3700X and an Radeon RX 5700 XT (Driver v21.11.1).
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