Printing to a PDF the whole thing is just blurred. I believe this happened after updating to catalina, but can't be totally sure as I don't tend to print that often. I also notice that the image is being scaled to only show part of it as below. If I go into range and scale and set this to Fit To Printable the image displays correctly and prints to PDF ok as below. I would have thought the default option was to scale the image to display correctly for the paper size by default.
I have a similar issue. When trying to print the preview is just all red and the printout comes out black. Printer Canon MG6350 OS - Mac Catalina 10.15 Affinity - 1.7.3