In recent beta many controls are now NOT loosing focus when user clicks outside of control. And even escape key do not remove focus out of control.
For example layer blending mode: click on it (in outliner), change blending - and click on any other layer in outliner. Or change the tool to another, for example. Blue rectangle will stay on control - focus not removed. Same with "Source" dropdown of patch tool - after changin source blue rectangle stays at control even if user clicks on canvas anywhere.
The problem with focus leads to much more painful keyboard interceptions. When focus stays in control - brush can not be changes with brackets (intercepted by control in focus - nothing happens with actual brush size) or user can not press space key to move the canvas (again, keypress intercepted by control and activates dropdown). Current behaviour of not removing focus from control (after changing the value in dropdowns) automatically - effectively cancels many of hotkeys.