I have been seeing something similar for some time now.
On the Mac I use for editing these docs [mostly a single page 1.5mb file] the [A] Mac will not complete a save, it appears to save but I get the save progress bar, which does not move and I have to crash Publisher V2 [fully patched]. Sometimes I have seen
Obviously I have restarted the Mac [A] which seems to make no difference.
My work around is to go to another [B] Mac and make the changes [with no issues] then go back to Mac [A] sometimes I can now open the file, but mostly I get the same frozen save progress bar.
I'm using iCloud to share workflow between Macs, Mainly because I need to make a PDF of a doc to put on the web and the app I'm using needs an older macOS [C].
The first Mac is a [A] 2021 MBP M1 Pro, the second is a [B] iMac Retina 5K 2017. and the "web" Mac is a [C] 2016 MBP.
Any help I can give, to help resolve this issue, would be forthcoming.
I really would like to get this finally sorted ;~}}