Some software (Artec Sudio 11, for example) comes with an XML file for the optimal settings for Wacom tablets for use with the software.
See http://101.wacom.com/UserHelp/en/ExpertSettings.htm.
I'm sure that someone at Serif is working on the Wacom/Affinity connection and knows the current best settings for using Wacom products with Affinity products. I'm am thinking mainly about the brush dynamics configurations.
It would be really helpful to have access to the xml file that your developers are currently using for testing Wacom products. I just got the new Wacom Mobile Studio pro at the same time as I got the Windows version of APh, So it's taking a lot of experimentation to work out the best way to use them together and I am not very knowledgeable about brush dynamics.