[Ability to export icon files (*.ico) in Designer]

+1

[Colour Picker Tool should recognise Transparency]

Not sure if this counts as a bug or a feature request, but currently the Colour Picker Tool does not recognise transparency.

 

(This makes it pretty hard to do icon design for non-retina screens in Affinity.)

[Font rendering: hinting and subpixel adjustments?]

I would also really like font hinting.

 

The Blending Ranges feature helps with pixel fonts (where you basically kill antialiasing), but as hevonen said, not a lot with regular fonts.

 

I realise the end of this problem is in sight – what with retina displays – but it'll still take some years before font hinting is no longer needed. It's still relevant for UI design, games, and web icons.