I am making the migration from Illustrator/Photoshop to Designer/Photo and finding that I will have to do some fiddling to get my Intuos 3 to function the way I need it to. it is doable, though. I guess this is the penalty for using a product longer than 5 years and never having a problem with it as I discovered that Wacom stopped supporting my version of the tablet, so the buttons are now useless (except the zoom bar moves the canvas up and down instead of zooming in and out). I really can't complain because it still works and has never been a problem. If I had to buy another tablet, it would definitely be a Wacom.
Operating on iMac/OSX El Capitan
I run an iMac going on its fourth year with El Capitan and Affinity Designer and Photo both work flawlessly.