Hello. I recently switched from Windows to Mac. I have the same, Windows keyboard that I'm using with Mac, and because of the reversed keyboard shortcuts (Ctrl,Alt and Win) I had to switch them around in the system settings for comfortable use.
The problem I have is that when I did that - Affinity cannot recognise that I'm pressing certain keys. It's especially annoying using the brush tool. The Alt (color picker) works good, but the Ctrl+Alt+Mouse Drag for scale/hardness does not work at all. When I try to do that, it just recognises Alt and switches to the color picker. What's interesting is that Ctrl + Space works as a magnifying glass, so the Ctrl button works even after the keyboard shortcut change but seems to have a hard time getting recognised when using it together with Alt.
I hope this can be fixed because I don't want to switch my system keyboard shortcuts every time I work in Affinity Photo