Vepar

@Vepar
Thank you for the feedback, and for confirming that the release of the 21.5.1 drivers has not resolved the problem.

Yup! It was the AMD drivers!
I used the AMD cleanup utility and installed the 21.3.1 version.
All of the Affinity programs work now!
 
Thank you @emmrecs01 and @Alfred for your help! I appreciate it! 😃

Yup! It was the AMD drivers!
I used the AMD cleanup utility and installed the 21.3.1 version.
All of the Affinity programs work now!
 
Thank you @emmrecs01 and @Alfred for your help! I appreciate it! 😃

Yup! It was the AMD drivers!
I used the AMD cleanup utility and installed the 21.3.1 version.
All of the Affinity programs work now!
 
Thank you @emmrecs01 and @Alfred for your help! I appreciate it! 😃

I’m glad you mentioned that. I hadn’t thought about hardware acceleration: try disabling it.

@Vepar
Further to what @Alfred says, exactly which AMD Radeon driver are you running?  The Radeon Adrenaline driver version 21.4.1 produced exactly the same problem for me.  Reverting to 21.3.1 resolved the problem.  (I see there is now version 21.5.1 but I have not installed that so don't know if AMD have found the problem. I know Serif were in contact with them.)
Since you can't actually launch the apps in order to disable Hardware Acceleration this FAQ will show you how to disable it when the apps are closed.
HTH
Jeff

I’m confused too!
Try clearing your user data for each of the apps. Press the Ctrl key on your keyboard and keep it held down while you launch the app: a ‘Clear User Data’ dialog will pop up, and if you press ‘Select All’ followed by ‘Clear’ you’ll restore the installation defaults.

Welcome to the Serif Affinity Forums, @Vepar.
I wonder whether this is the problem:
Instead of performing fresh installs you should have been able to simply input the product keys when launching the trial versions (as an alternative to choosing the ‘Continue trial’ option). Did you reset your PC during the uninstallation/reinstallation procedure?