@Mark Ingram Sure, I'll do my best - I think my setup might be a bit exotic. First, here's some device id's for the card:
The actual card in question is this one from Sapphire: https://www.sapphiretech.com/en/consumer/pulse-rx-580-8g-g5
It's inside of this Razer Core X enclosure: https://www.razer.com/gaming-egpus/razer-core-x/RC21-01430100-R3U1
..and finally the it's connected through a Dell 3GMVT TB16 Thunderbolt 3 Dock to a Dell XPS 15 9560 laptop. Let me know if I can get you anything else. I can try taking the dock out of the equation and hooking up to the GPU directly if you think it might help narrow things down.
UPDATE:
I disconnected the dock and connected directly to the GPU and the issue didn't occur. What's worse, is now when I hooked everything back up the way it was before, it doesn't happen in theat configuration any longer either! On the one hand, it's nice things are working properly for me now. On the other hand, I wish I had more helpful info for the next person.