Thanks for the replies. Firstly, the forum admin team were on the case very quickly about my brainless username! Hopefully my email address hasn’t already been harvested by thousands of spammers…
Regarding the file format question, it’s partly hypothetical because I’ve only ever shot RAW in all my years of serious digital photography and processed the end result in either Lightroom or Capture One Pro and that will continue. All my highlight recovery, tone mapping, colour grading, etc. is done that way. Pixel-based editing (if that’s the right term) is quite new to me and Affinity Photo is quite obviously the biggest bargain in the photo editing world! It’s worth the price for the in-painting brush alone. I find I’m using it far more than I thought and the question quickly occurred to me that maybe working on my jpegs exported from Capture One wasn’t necessarily the best approach. If the Affinity Photo experts think even pixel edits are best done on a TIFF file rather than a JPEG then that’s the workflow I will adopt. It’s hard to believe anyone would expect good results doing shadow detail retrieval on a JPEG, but I wasn’t sure if that ‘rule’ extended to more creative editing work.